Cross club
This “only in Prague” club has been through quite a bit of evolution. First opened as a members-only club because of bureaucratic setbacks, Cross Club then became one of the grungiest, wildest establishments around. Since then, there have been some rumored legal issues and this chameleon of a club has begun to clean up its act, as evidenced by the new upstairs chill-out area (which makes a person wonder- where does the staff live now?) This clean, bright, bamboo area has nothing to do with what lies underneath. In the dark, labyrinthine club below, anything goes. The lights hypnotize as they bubble and change colors, the ashtrays are simply massive bowls attached to the tables, twisted metal moves, spider like, on the walls and ceiling. Cross Club is a home for hippies and hipsters, druggies and drinkers, artists and muses – anyone seeking laid-back, unregulated fun in a land unlike any other.

Lucerna Music Bar
Best 80’s club in Prague.
One of the oldest clubs in Prague with varied music program: rock, hip hop, reggae,  and famous 80′.-90.’ disco each friday and saturday

Palác Akropolis

Centre of independent culture offering unique music, theatre and art projects.
Since its establishment Palác Akropolis have been presenting domestic interprets and also foreign stars from many fields of musical and theatre scene.

Various programmes full of many famous names are completed with not so famous or just beginning artists. There are approximately 950 cultural events annually.

Roxy is a popular nightclub that attracts big name DJ’s. Music spans all genres, but is lot more hard core than most other clubs in Prague. Drum ‘n’ Bass, Jungle and Techno often feature here.

Undergorund club. Through the whole week HC, Punk, Ska and alternative acts from all around the world. Club is located at student area on the hill Petrin/Strahov (near Strahovsky stadion), reasonable prices, veggie pizza on special recipe, established underground and writter of czech punk and underground movement history since 1969!!! Koleje CVUT Strahov, Chaloupeckeho 7.

Klub Lávka

Tequila bar, music from the 1960s to present. On a cold winters night, Lavka Bar & Club is a good place for a drink and a dance. On a hot summer’s evening though, Lavka is just about the best night out in Prague, bar none.Lavka sits right on the banks of the River Vltava, next to Charles Bridge. With terraces both at the back and at the front, there are stunning views to be enjoyed, across the water and up to Prague Castle. This supreme location attracts a lively tourist-heavy crowd, although many Czechs also view this as good club to party the night away in. The music tends to get more up to date, and more hardcore, as the night progresses, and so involves some good party music early on, pushing on to today’s best dance tunes once the dance floor is ready for it. In the summer, Lavka’s great riverside terrace at the rear can be packed with revellers, enjoying the views over the water, drinking the cool draught Pilsner Urquell, and swaying to the music. Lavka is not all club though. During the day and early evening, you can just pop along for a quiet drink, whether alcoholic or just a coffee, and enjoy the views. Address: Novotného lávka 1, Prague 1. Getting there: Metro A to Staroměstské náměstí
Hours: 9:30 p.m. – 5 a.m.

Rock Café

The club is not only a venue for concerts but also provides space for a gallery, CD shop and cinema.Rock Café is divided into a few sections. In the first section you’ll find a pub, open the whole day and evening, with comfy sofas and club chairs. In the other section is the Gung-Ho CD shop, where you can buy metal and underground music and also book tickets for some metal concerts. The bar, an internet café and the stage for concerts are located underground. The stage is an air-conditioned huge black hall with a capacity for a few hundred people. Occasionally there are also some music contests, mainly of young unknown bands that hope to be noticed by the organising sponsor.
After recent renovations the capacity of the club and bar space has increased.

Radost FX
One of the most popular dance clubs in Prague. Radost FX is the home of House, R&B/soul and Hip Hop music. Extravagant parties, eccentric decor make this one of the most popular hot spots in the city.Whatever your party apetite may be there is a night for you. Plastique is a hipster paradise with raunchy electric tunes and trendy fashion…. Lollypop is the biggest and best gay friendly party with a new themw every month. Soultrain provides sexy and soultry sounds while FX Bounce bangs out urban beats. Prague’s first and favorite place to party.
Address: Bělehradská 120, Prague 2
Getting there: Metro C to IP Pavlova

Malostranská beseda

Besides hosting random nights of some good jazz, the beseda (“meeting place”) on the restored baroque main square in Malá Strana once acted as the district’s town hall. The mix of bands varies, so check the Prague Post to see if the beseda is playing your tune. On the second floor, the club consists of little more than two smallish rooms; one holds the bar, the other a stage on which live bands perform most every night. You’ll do more sitting than dancing here. The bar is open daily from 5 to 8pm, after 8pm only to ticket holders, and the music usually begins at 8:30pm.